Sale! UROFIL

UROFIL

Sanitpharma

911002121

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Supplement, 30 modified-release tablets
Italian pharmacode: 911002121

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Urofil is a food supplement containing Cranberry, Methionine and Pomegranate.

  • Cranberry (Vaccinium macrocarpon) juice and cranberry extracts are a source of polyphenols including proanthocyanidins, flavonoids and quercetin known to have anti-inflammatory and antibacterial potential. Recent studies showed that cranberry significantly reduced the incidence of urinary tract infections and it is effective particularly for individuals with recurrent infections. Research suggested that its mechanism of action preventing bacterial adherence to host cell surface membranes.
  • Methionine: the kidneys can use L-methionine to acidify the urine and prevent the formation of kidney stones. Urine with a pH value of between 4 and 6 can inhibit the growth of bacteria in cases of cystitis, as most bacteria cannot survive in an acidic environment. Acid pH can also optimise the effects of many antibiotics.
  • Pomegranate: rich source of natural antioxidant compounds such as flavonoids and anthocyanins that help the body to counteract free radicals. Pomegranate is also rich with Ellagitannins such as Ellagic Acid and Punicalagin that have been identified as compounds capable of inhibit the proliferation of human cancer cells and modulate inflammatory subcellular signaling pathways and apoptosis

How to use
We recommend 1 or 2 tablets a day if required. Drink abundantly during the day.


References

Seeram NP, Henning SM, Zhang Y, Suchard M, Li Z, Heber D., Pomegranate juice ellagitannin metabolites are present in human plasma and some persist in urine for up to 48 hours. J Nutr. 2006 Oct;136(10):2481-5.

Khan N, Afaq F, Kweon MH, Kim K, Mukhtar H., Oral consumption of pomegranate fruit extract inhibits growth and progression of primary lung tumors in mice. Cancer Res. 2007 Apr 1;67(7):3475-82. 

Lansky EP, Newman RA., Punica granatum (pomegranate) and its potential for prevention and treatment of inflammation and cancer. J Ethnopharmacol. 2007 Jan 19;109(2):177-206.

Pantuck AJ, Leppert JT, Zomorodian N, Aronson W, Hong J, Barnard RJ, Seeram N, Liker H, Wang H, Elashoff R, Heber D, Aviram M, Ignarro L, Belldegrun A., Phase II study of pomegranate juice for men with rising prostate-specific antigen following surgery or radiation for prostate cancer. Clin Cancer Res. 2006 Jul 1;12(13):4018-26. 

Howell AB., Bioactive compounds in cranberries and their role in prevention of urinary tract infections. Mol Nutr Food Res. 2007 

Di Martino P, Agniel R, David K, Templer C, Gaillard JL, Denys P, Botto H., Reduction of Escherichia coli adherence to uroepithelial bladder cells after consumption of cranberry juice: a double-blind randomized placebo-controlled cross-over trial. World J Urol. 2006 Feb;24(1):21-7 

Jacobs D, Heimbach D, Hesse A., Chemolysis of struvite stones by acidification of artificial urine: an in vitro study. Scand J Urol Nephrol. 2001 Oct;35(5):345-9.

Hesse A, Heimbach D., Causes of phosphate stone formation and the importance of metaphylaxis by urinary acidification: a review. World J Urol. 1999 Oct;17(5):308-15.

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